Why waking up between 2am and 3am could actually mean something serious

He added that the issue went far beyond brief awakenings. Some nights, he didn’t sleep at all, lying awake until morning. “It felt like torture,” he said.

Why that time matters

Dr. Berg later focused specifically on 2 a.m., explaining how the body’s circadian rhythm is meant to work. Normally, cortisol is lowest around 2 a.m. and peaks around 8 a.m. In his case, the cycle was reversed—he felt alert at night and exhausted in the morning.

Long-term sleep deprivation, he noted, has been linked to serious conditions including heart disease, dementia, and diabetes.
Ways to lower cortisol at night
Dr. Berg says there are strategies that may help reduce cortisol levels while sleeping and prevent those early-morning awakenings. One of the most important, he says, is magnesium.

A lack of magnesium can cause muscle tightness, cramps, and heightened cortisol. He explained that stiffness in the back or leg cramps—especially when pointing the toes—can be signs of deficiency.
Magnesium also supports muscle relaxation, calms the nervous system, and can help reduce anxiety and irritability. Dr. Berg recommends taking magnesium supplements in the evening before bed.

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