While localized inflammation is a normal part of the healing process, certain symptoms indicate that the infection is spreading and requires professional intervention. The most alarming of these is a red streak traveling away from the wound and up your limb, which suggests the infection is moving into your lymphatic system. Additionally, if you develop a fever, experience severe or escalating pain, or if the local symptoms persist and worsen despite your home care efforts, it is time to see a doctor. When in doubt, it is always safer to seek professional medical advice than to wait and risk severe complications.