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  • Thyroid or other hormonal disorders
  • Certain medications, including some corticosteroids and hormone treatments
  • Rarely, underlying medical conditions that require prompt evaluation

Because several different conditions can contribute to these skin changes, a medical assessment is important to determine the underlying cause.

Why Early Evaluation Matters

In some people, acanthosis nigricans may appear before other signs of insulin resistance or type 2 diabetes become noticeable. Identifying the condition early gives healthcare providers an opportunity to evaluate overall metabolic health and recommend appropriate lifestyle changes or treatment if needed.

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